BDBM50243156 CHEMBL446570::cis-N-methyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine

SMILES CN[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12

InChI Key InChIKey=WPKZZLMFEYGCJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243156   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243156(cis-N-methyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1...)
Affinity DataIC50: 660nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243156(cis-N-methyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243156(cis-N-methyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed