BDBM50243157 CHEMBL521392::cis-N,N-dimethyl-3-(o-tolyloxy)-2,3-dihydro-1H-inden-1-amine

SMILES CN(C)[C@@H]1C[C@H](Oc2ccccc2C)c2ccccc12

InChI Key InChIKey=NBLMTDPDGYITGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243157   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243157(cis-N,N-dimethyl-3-(o-tolyloxy)-2,3-dihydro-1H-ind...)
Affinity DataIC50: 150nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243157(cis-N,N-dimethyl-3-(o-tolyloxy)-2,3-dihydro-1H-ind...)
Affinity DataIC50: 300nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243157(cis-N,N-dimethyl-3-(o-tolyloxy)-2,3-dihydro-1H-ind...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed