BDBM50243271 CHEMBL453321::trans-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-1-amine

SMILES Cc1ccccc1O[C@@H]1CC[C@@H](N)c2ccccc12

InChI Key InChIKey=WZVJYHZPOKMITP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243271   

TargetSodium-dependent noradrenaline transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243271(trans-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243271(trans-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of dopamine uptake at human DAT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243271(trans-4-(o-tolyloxy)-1,2,3,4-tetrahydronaphthalen-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of serotonin uptake at human SERT in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed