BDBM50243366 1-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea::CHEMBL452284

SMILES Nc1c(cnc2ccnn12)-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1

InChI Key InChIKey=GXDRFZPZFZKPSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243366   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50243366(1-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)...)
Affinity DataIC50: 14nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50243366(1-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed