BDBM50243487 CHEMBL4091668

SMILES O=c1[nH]ccc2cc(F)c(NS(=O)(=O)c3ccc(N4C[C@@H](O)C(F)(F)C4)s3)cc12

InChI Key InChIKey=CQYXSDSLQRMVCQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243487   

LigandChemical structure of BindingDB Monomer ID 50243487BDBM50243487(CHEMBL4091668)
Affinity DataIC50: 12nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50243487BDBM50243487(CHEMBL4091668)
Affinity DataEC50:  27nMAssay Description:Inhibition of AICARFT in human NCI-H460 cells assessed as increase in ZMP levels using low folate media after 16 hrs by LC-MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed