BDBM50243943 1-Biphenyl-4-yl-3-aza-bicyclo[3.1.0]hexane::CHEMBL505313

SMILES C1C2CNCC12c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=FKKPHPHBDNQCCQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243943   

TargetSodium-dependent serotonin transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243943(1-Biphenyl-4-yl-3-aza-bicyclo[3.1.0]hexane | CHEMB...)
Affinity DataIC50: 160nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243943(1-Biphenyl-4-yl-3-aza-bicyclo[3.1.0]hexane | CHEMB...)
Affinity DataIC50: 360nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243943(1-Biphenyl-4-yl-3-aza-bicyclo[3.1.0]hexane | CHEMB...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed