BDBM50244242 CHEMBL4082936

SMILES CCOc1ccc(Cc2nc3cc(ccc3n2CCN2CCCCC2)C(=O)N(CC)CC)cc1

InChI Key InChIKey=JRJWAARCOBEVOL-UHFFFAOYSA-N

Data  4 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50244242   

TargetCannabinoid receptor 2(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataKi:  188nMAssay Description:Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataKi:  188nMAssay Description:Binding affinity to human CB2 receptor stably expressed in HEK cells assessed as inhibition constant by GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataKi:  556nMAssay Description:Displacement of [3H]-Diprenorphine from human mu opioid receptor expressed in HEK293-TSA cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataKi:  556nMAssay Description:Displacement of [3H]-Diprenorphine from human mu opioid receptor expressed in HEK293-TSA cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human BChE using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of human BChE using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Horse)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of equine serum BChEMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Horse)
Cnr-Institute of Crystallography

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of equine BChE using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Human)
Julius Maximilian University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244242(CHEMBL4082936)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed