BDBM50244275 1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-4-yl]methyl}-3H-spiro[2-benzofuran-1,4'-piperidine]::CHEMBL470951

SMILES Cc1nn(cc1CN1CCC2(CC1)OCc1ccccc21)-c1ncccc1C

InChI Key InChIKey=SLRRKIAIUARVQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244275   

TargetMu-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244275(1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50: 4.40E+3nMAssay Description:Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244275(1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244275(1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of [35S]MK499 from human ERG in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed