BDBM50244391 4-(4-chloro-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-2,5-dihydro-1H-pyrrol-3-ylamino)benzoic acid::CHEMBL488825

SMILES OC(=O)c1ccc(cc1)N=C1C(Cl)C(=O)N(C1=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=OBMWWSFXCPAKLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244391   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50244391(4-(4-chloro-2,5-dioxo-1-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurementsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed