BDBM50244578 CHEMBL4076755

SMILES CCCC[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](C\C=C/C[C@H](NC(=O)[C@@H]2CCCN2C1=O)C(O)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCC(=O)N1

InChI Key InChIKey=HQRYNSJXPXVUBY-BQELOSIBSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244578   

TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50244578(CHEMBL4076755)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-[Nle75, Tyr77] Pyr1-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes after 1 hr by gamma-counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50244578(CHEMBL4076755)
Affinity DataEC50:  272nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50244578(CHEMBL4076755)
Affinity DataEC50:  469nMAssay Description:Binding affinity against dopamine receptor D2 from rat striatal homogenates using [3H]YM-09151-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50244578(CHEMBL4076755)
Affinity DataEC50:  19nMAssay Description:Binding affinity against human bradykinin receptor B2 using [3H]bradykinin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed