BDBM50245035 CHEMBL488704::N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine

SMILES COc1cc2nc(nc(Nc3cccc(Br)c3)c2cc1OC)N1CCC(CC1)N1CCCC1

InChI Key InChIKey=HJQMVMHBYLQUMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245035   

TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245035(N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-...)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50245035(N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-...)
Affinity DataIC50: 510nMAssay Description:Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed