BDBM50245908 CHEMBL518822::N3-(2,6-dimethylphenyl)-1-(2-morpholinoethyl)-N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine

SMILES Cc1cccc(C)c1Nc1nn(CCN2CCOCC2)c2nc(Nc3ccccc3)ncc12

InChI Key InChIKey=LDAWSYOWVKTXAN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245908   

TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245908(CHEMBL518822 | N3-(2,6-dimethylphenyl)-1-(2-morpho...)
Affinity DataKi:  50nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245908(CHEMBL518822 | N3-(2,6-dimethylphenyl)-1-(2-morpho...)
Affinity DataKi:  70nMAssay Description:Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed