BDBM50246251 CHEMBL488080::N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-yl)isobutyramide

SMILES COc1ccc(CNc2ncnc3c(CCO)c(OC)c(NC(=O)C(C)C)cc23)cc1Cl

InChI Key InChIKey=XHXWMODRCZLVMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246251   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246251(N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxye...)
Affinity DataIC50: 21nMAssay Description:Inhibition of bovine PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246251(N-(4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxye...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human recombinant PDE11More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed