BDBM50246413 CHEMBL509012::N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)-2-isopropylpiperidine-4-carboxamide

SMILES CC(C)C1CC(CCN1)C(=O)Nc1ncc(SCc2ncc(o2)C(C)(C)C)s1

InChI Key InChIKey=SYGZEVSXMXZNJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246413   

TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246413(N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK2/Cyclin A by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246413(N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-...)
Affinity DataIC50: 810nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed