BDBM50246802 CHEMBL4077215
SMILES CCc1c[nH]c2ncnc(N[C@H]3CC[C@@H](CC3)N(C)C)c12
InChI Key InChIKey=REPOYTYLMHHIGZ-JOCQHMNTSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50246802
Affinity DataIC50: 63nMAssay Description:Inhibition of IRAK4 in human KARPAS299 cells assessed as reduction in IL-1 stimulated IRAK4 phosphorylation at Thr345/Ser346 residues preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant full length His-tagged human IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair