BDBM50246921 CHEMBL4077043

SMILES COc1cc(C)[nH]c(=O)c1CN1CCc2c(Cl)cc(C(OC)C3(C)COC3)c(Cl)c2C1=O

InChI Key InChIKey=MCMKAVXRKBSUCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246921   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Wuxi Apptec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246921BDBM50246921(CHEMBL4077043)
Affinity DataIC50: 253nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Wuxi Apptec

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246921BDBM50246921(CHEMBL4077043)
Affinity DataIC50: 253nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMed