BDBM50246946 5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid::CHEMBL508948

SMILES OC(=O)c1cc(\C=C\c2ccccc2)ccc1O

InChI Key InChIKey=JZELPKQSIAYAOP-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50246946   

TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246946BDBM50246946(5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid | CHEM...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human Gal4-HNFalpha-LBD expressed in HEK293T cells transfected with pFR-Luc/pRLSV40 assessed as relative luminescence measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246946BDBM50246946(5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid | CHEM...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246946BDBM50246946(5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid | CHEM...)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of PTP SHP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246946BDBM50246946(5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid | CHEM...)
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed