BDBM50247641 CHEMBL4077296

SMILES OC12CC3CC(C1)CC(NCc1cc(C4CC4)on1)(C3)C2

InChI Key InChIKey=KPGNNUHGVDHBFR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247641   

TargetCytochrome P450 1A2(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247641BDBM50247641(CHEMBL4077296)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 10 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247641BDBM50247641(CHEMBL4077296)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247641BDBM50247641(CHEMBL4077296)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 10 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247641BDBM50247641(CHEMBL4077296)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50247641BDBM50247641(CHEMBL4077296)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed