BDBM50248047 CHEMBL503524::N-(3-fluoro-4-(2-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide
SMILES Fc1cc(NC(=O)N2CCN(C2=O)c2ccccc2)ccc1Oc1ccnc2cc(sc12)-c1cn(CCN2CCCC2)cn1
InChI Key InChIKey=HPCRKJXLHNPYNB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50248047
Affinity DataIC50: 35nMAssay Description:Inhibition of GST-fused recombinant c-Met (unknown origin) catalytic domain expressed in baculovirus-infected Trichoplusia ni Hi5 cells after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of TPR-fused Met (unknown origin) phosphorylation expressed in human 293T cells by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-fused recombinant VGFR2 (unknown origin) catalytic domain expressed in baculovirus-infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair