BDBM50248226 4-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-1-phenyl-1H-pyrazole-3-carboxylic acid::CHEMBL474149

SMILES Cc1oc(nc1CCOc1cccc(Cc2cn(nc2C(O)=O)-c2ccccc2)c1)-c1ccccc1

InChI Key InChIKey=HZIAVVQCQZRYKZ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248226   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50248226(4-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataEC50:  311nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in HEK293 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50248226(4-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataEC50:  156nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in HEK293 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50248226(4-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataIC50:  140nMAssay Description:Binding affinity to PPARalpha (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50248226(4-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to PPARgamma (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed