BDBM50248815 2-{3-[(Ethylmethylamino)methyl]benzyl}-5,6-dimethoxy-2,3-dihydroinden-1-one::CHEMBL515891

SMILES CCN(C)Cc1cccc(CC2Cc3cc(OC)c(OC)cc3C2=O)c1

InChI Key InChIKey=CQZPKEFEHXEQPI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248815   

TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50248815(2-{3-[(Ethylmethylamino)methyl]benzyl}-5,6-dimetho...)
Affinity DataKi:  507nMAssay Description:Binding affinity to acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetAcetylcholinesterase(Rat)TBA
LigandPNGBDBM50248815(2-{3-[(Ethylmethylamino)methyl]benzyl}-5,6-dimetho...)
Affinity DataIC50: 685nMAssay Description:Inhibition of acetylcholinesterase in Rattus norvegicus (rat) cortex by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetAcetylcholinesterase(Rat)TBA
LigandPNGBDBM50248815(2-{3-[(Ethylmethylamino)methyl]benzyl}-5,6-dimetho...)
Affinity DataIC50: 690nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248815(2-{3-[(Ethylmethylamino)methyl]benzyl}-5,6-dimetho...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed