BDBM50248818 2-{3-[(Diethylamino)methyl]benzyl}-5,6-dimethoxy-2,3-dihydroinden-1-one::CHEMBL472813

SMILES CCN(CC)Cc1cccc(CC2Cc3cc(OC)c(OC)cc3C2=O)c1

InChI Key InChIKey=MDZMZBMFJIRMKC-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248818   

TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50248818(2-{3-[(Diethylamino)methyl]benzyl}-5,6-dimethoxy-2...)
Affinity DataKi:  22nMAssay Description:Binding affinity to acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248818(2-{3-[(Diethylamino)methyl]benzyl}-5,6-dimethoxy-2...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248818(2-{3-[(Diethylamino)methyl]benzyl}-5,6-dimethoxy-2...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of acetylcholinesterase in Rattus norvegicus (rat) cortex by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetCarboxylic ester hydrolase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248818(2-{3-[(Diethylamino)methyl]benzyl}-5,6-dimethoxy-2...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed