BDBM50249132 (4-((1H-imidazol-2-yl)methyl)piperidin-1-yl)(4'-fluorobiphenyl-4-yl)methanone::CHEMBL473185

SMILES Fc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(Cc2ncc[nH]2)CC1

InChI Key InChIKey=QSLPZMYMMHGUKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249132   

Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249132((4-((1H-imidazol-2-yl)methyl)piperidin-1-yl)(4'-fl...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249132((4-((1H-imidazol-2-yl)methyl)piperidin-1-yl)(4'-fl...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed