BDBM50249194 (15S)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaene-15-carboxamide::CHEMBL474576

SMILES C[C@]1(C(=O)Nc2nccs2)CC2c3ccccc3C1c1ccccc12

InChI Key InChIKey=QYEYUIJWYCBKBG-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249194   

TargetGlucocorticoid receptor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249194BDBM50249194((15S)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataKi:  26.2nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249194BDBM50249194((15S)-15-methyl-N-(1,3-thiazol-2-yl)tetracyclo[6.6...)
Affinity DataEC50:  544nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed