BDBM50249521 CHEMBL4096346

SMILES CCc1cc2c(cc1Cn1c(C(=O)O)c(Cc3cccc(-c4nnn[nH]4)c3)c(=O)c3cc(O)ccc31)OCO2

InChI Key InChIKey=GWJFUFDQTPBTHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249521   

TargetEndothelin-1 receptor(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249521BDBM50249521(CHEMBL4096346)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at ETA receptor (unknown origin) expressed in membranes by radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249521BDBM50249521(CHEMBL4096346)
Affinity DataIC50: 1.62E+4nMAssay Description:Antagonist activity at ETB receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed