BDBM50249534 CHEMBL4068786

SMILES CCc1cc2c(cc1Cn1c(C(=O)O)c(Cc3cccc(-c4nnn[nH]4)c3)c(=O)c3cc(OCC4CCC4)ccc31)OCO2

InChI Key InChIKey=VQKDQUCIEIPABF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249534   

TargetEndothelin-1 receptor(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249534BDBM50249534(CHEMBL4068786)
Affinity DataIC50: 279nMAssay Description:Antagonist activity at ETA receptor (unknown origin) expressed in membranes by radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
St. John'S University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249534BDBM50249534(CHEMBL4068786)
Affinity DataIC50: 1.44E+3nMAssay Description:Antagonist activity at ETB receptor (unknown origin) expressed in HEK293T cells measured after 30 mins by CCF4-AM dye based GeneBlazer FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed