BDBM50250450 CHEMBL4103328

SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2CCC[C@@]3(OCc2ccccc2)[C@H]1C5

InChI Key InChIKey=RDZUOGAZZXZDPY-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250450   

TargetMu-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250450BDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.0480nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250450BDBM50250450(CHEMBL4103328)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250450BDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250450BDBM50250450(CHEMBL4103328)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed