BDBM50250451 CHEMBL4088589

SMILES CO[C@@]12CCC[C@]3(C)Oc4c(O)ccc5c4[C@@]31CCN(C)[C@@H]2C5

InChI Key InChIKey=IWNLIUUGJPKDCB-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250451   

TargetMu-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250451BDBM50250451(CHEMBL4088589)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-DAMGO from recombinant human MOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250451BDBM50250451(CHEMBL4088589)
Affinity DataEC50:  3nMAssay Description:Agonist activity at recombinant human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250451BDBM50250451(CHEMBL4088589)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]-HS665 from recombinant human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250451BDBM50250451(CHEMBL4088589)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-diprenorphine from recombinant human DOR expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2019
Entry Details Article
PubMed