BDBM50250582 CHEMBL4068654

SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O

InChI Key InChIKey=SFGAMHAXMGIWOF-IQBDGJDESA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50250582   

TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataIC50:  118nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataIC50:  360nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50:  521nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50:  128nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50250582(CHEMBL4068654)
Affinity DataIC50:  36nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed