BDBM50250691 CHEMBL4062709::US10961200, Compound 166::US11247971, Cmpd ID 166

SMILES NS(=O)(=O)c1ccc(Oc2c(nn(-c3nc(cs3)C(O)=O)c2C2CC2)-c2ccccc2)cc1

InChI Key InChIKey=UIHUZUOXAYYUNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250691   

TargetL-lactate dehydrogenase A chain(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50250691(CHEMBL4062709 | US10961200, Compound 166 | US11247...)
Affinity DataIC50: <100nMAssay Description:Test compounds were placed in a Greiner Bio-One (Monroe, N.C.) 1536-well black solid bottom assay plate. 200 millimolar (mM) Tris HCl, pH 7.4, 100 mi...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetL-lactate dehydrogenase A chain(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50250691(CHEMBL4062709 | US10961200, Compound 166 | US11247...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed