BDBM50250848 CHEMBL4059676

SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)-c1ccccc1)C(F)(F)F

InChI Key InChIKey=ZWEMGIQYCJPRLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250848   

TargetMonoglyceride lipase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250848(CHEMBL4059676)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of human recombinant MAGL using 7-HCA as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFatty-acid amide hydrolase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250848(CHEMBL4059676)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed