BDBM50250937 CHEMBL4076821

SMILES NC(=O)c1cn(nc1Nc1ccccc1)[C@H]1CCCC[C@@H]1C#N

InChI Key InChIKey=DLZJFUWJIGTHDZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250937   

TargetTyrosine-protein kinase JAK1(Human)
Merck

Curated by ChEMBL

LigandBDBM50250937(CHEMBL4076821)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 catalytic domain expressed in baculovirus expression system using LCB-EQEDEPEGDYFEWLW-NH2 as substrat...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/27/2019
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50250937(CHEMBL4076821)Copy SMILESCopy InChI

Affinity DataIC50: 6.00E+4nMAssay Description:Displacement of [35S]-MK499 from human ERG expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/27/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL