BDBM50251240 CHEMBL4082457

SMILES [#6]-[#8]-c1cc(-[#8])cc(-[#6]-[#6]-c2ccc(-[#8]-[#6])c(-[#8])c2-[#6]\[#6]=[#6](\[#6])-[#6])c1

InChI Key InChIKey=AEGVHFKABYQHLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251240   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50251240(CHEMBL4082457)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 pre-incubated for 10 mins before arachidonic acid substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50251240(CHEMBL4082457)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cells microsomal membranes assessed as reduction in conversion of PGH2 to PGE2 pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed