BDBM50251491 6-((1S,5R,6s)-6-(2-((S)-2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethylamino)-3-aza-bicyclo[3.1.0]hexan-3-yl)nicotinonitrile::CHEMBL480712

SMILES FC1(F)C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1ccc(cn1)C#N

InChI Key InChIKey=UVFFUNUQBNLABG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251491   

TargetDipeptidyl peptidase 4(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251491(6-((1S,5R,6s)-6-(2-((S)-2-cyano-4,4-difluoropyrrol...)
Affinity DataIC50: 93nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251491(6-((1S,5R,6s)-6-(2-((S)-2-cyano-4,4-difluoropyrrol...)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251491(6-((1S,5R,6s)-6-(2-((S)-2-cyano-4,4-difluoropyrrol...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251491(6-((1S,5R,6s)-6-(2-((S)-2-cyano-4,4-difluoropyrrol...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251491(6-((1S,5R,6s)-6-(2-((S)-2-cyano-4,4-difluoropyrrol...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of PPCEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed