BDBM50251853 (2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluoromethyl)pyrimidin-2-yl)-3-aza-bicyclo[3.1.0]hexan-6-ylamino)acetyl)pyrrolidine-2-carbonitrile::CHEMBL482262

SMILES F[C@H]1C[C@@H](C#N)N(C1)C(=O)CN[C@@H]1[C@H]2CN(C[C@@H]12)c1nccc(n1)C(F)(F)F

InChI Key InChIKey=CCAHGNFSCCVYCY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50251853   

TargetDipeptidyl peptidase 4(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251853((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...)
Affinity DataIC50: 181nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251853((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251853((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...)
Affinity DataIC50: 5.42E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251853((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Ranbaxy Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50251853((2S,4S)-4-fluoro-1-(2-((1S,5R,6s)-3-(4-(trifluorom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PPCEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed