BDBM50252058 CHEMBL482096::Ethyl 2-oxo-2-{3-[(quinoline-3-carbonyl)-amino]-phenyl}-ethyl trithiocarbonate

SMILES CCSC(=S)SCC(=O)c1cccc(NC(=O)c2cnc3ccccc3c2)c1

InChI Key InChIKey=BEKGFNTZGMLIIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252058   

TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252058(Ethyl 2-oxo-2-{3-[(quinoline-3-carbonyl)-amino]-ph...)
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252058(Ethyl 2-oxo-2-{3-[(quinoline-3-carbonyl)-amino]-ph...)
Affinity DataIC50: 592nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed