BDBM50252923 (S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H,3H)-dione::CHEMBL508818

SMILES N[C@@H](Cn1c2ccccc2c(=O)[nH]c1=O)C(O)=O

InChI Key InChIKey=ZYJNLAXHRRAHRR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252923   

TargetGlutamate receptor ionotropic, kainate 1(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252923((S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H...)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor 1(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252923((S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H...)
Affinity DataKi:  2.39E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor 2(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252923((S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H...)
Affinity DataKi:  3.39E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252923((S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H...)
Affinity DataKi:  6.91E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor 4(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252923((S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H...)
Affinity DataKi:  1.57E+4nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252923((S)-1-(2'-Amino-2'-carboxyethyl)quinazoline-2,4(1H...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed