BDBM50253070 (1R,2R)-N-(1-cyanocyclopropyl)-5,5-difluoro-2-(4-(4-(methylsulfonyl)phenyl)-1H-pyrazol-3-yl)cyclohexanecarboxamide::CHEMBL492655

SMILES CS(=O)(=O)c1ccc(-c2cn[nH]c2[C@@H]2CCC(F)(F)C[C@H]2C(=O)NC2(C#N)CC2)cc1

InChI Key InChIKey=MUIUCPDRGPTQJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253070   

TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50253070BDBM50253070((1R,2R)-N-(1-cyanocyclopropyl)-5,5-difluoro-2-(4-(...)
Affinity DataIC50: 18.6nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed