BDBM50253252 CHEMBL4086526

SMILES CO[C@H]1CC[C@@H](CC1)NC(=O)c1nc(-c2nc(-c3cnc4ccccn34)c(C)nc2N)n(C)n1

InChI Key InChIKey=PBFNEINMGRSMKE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50253252   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50253252(CHEMBL4086526)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/6/2019
Entry Details Article
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