BDBM50253949 CHEMBL4100667

SMILES Cl.Cl.CC(C)Cc1nc(C)c(C(=O)OCc2ccc(cc2)C(O)=O)c(-c2ccc(C)cc2)c1CN

InChI Key InChIKey=NJYKWCPERDRYQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253949   

TargetDipeptidyl peptidase 4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253949(CHEMBL4100667)
Affinity DataIC50:  17nMAssay Description:Inhibition of human DPP4 purified from Caco2 cells pre-incubated for 15 mins before Gly-Pro-pNA substrate addition and measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDipeptidyl peptidase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50253949(CHEMBL4100667)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FLAG-tagged human DPP8 expressed in 293-F cells pre-incubated for 20 mins before Gly-Pro-pNA substrate addition and measured after 90 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed