BDBM50254005 3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine::CHEMBL517417

SMILES Nc1nc(-c2ccco2)c2nnn(Cc3cccc(c3)C#N)c2n1

InChI Key InChIKey=LMKCBJGIOMTJNM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254005   

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254005(3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  3.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254005(3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  132nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254005(3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  630nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254005(3-(3-Cyanobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4...)
Affinity DataKi:  693nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed