BDBM50254352 7-(2-Furyl)-3-(3-pyridylmethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine::CHEMBL449596

SMILES Nc1nc(-c2ccco2)c2nnn(Cc3cccnc3)c2n1

InChI Key InChIKey=QFWCQCHUXCNVBH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254352   

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254352(7-(2-Furyl)-3-(3-pyridylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  14.5nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254352(7-(2-Furyl)-3-(3-pyridylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  225nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254352(7-(2-Furyl)-3-(3-pyridylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  931nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254352(7-(2-Furyl)-3-(3-pyridylmethyl)-3H-[1,2,3]triazolo...)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed