BDBM50254433 1-(2-methyl-5-(4-methylpiperazin-1-ylsulfonyl)furan-3-yl)-3-phenylurea::CHEMBL469114

SMILES CN1CCN(CC1)S(=O)(=O)c1cc(NC(=O)Nc2ccccc2)c(C)o1

InChI Key InChIKey=VJVJSRDFIMSFEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254433   

TargetEndothelial lipase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254433(1-(2-methyl-5-(4-methylpiperazin-1-ylsulfonyl)fura...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of endothelial lipase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Rattus norvegicus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50254433(1-(2-methyl-5-(4-methylpiperazin-1-ylsulfonyl)fura...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Lipoprotein lipase from adipose tissue of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed