BDBM50254510 3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL511691

SMILES CC1C2C(=O)c3ccc(C(N)=O)cc3C1(C)CCN2CC1CC1

InChI Key InChIKey=UZBPHRWPBOWFLU-UHFFFAOYSA-N

Data  2 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254510   

TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254510BDBM50254510(3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254510BDBM50254510(3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254510BDBM50254510(3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,...)
Affinity DataEC50:  4.20nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254510BDBM50254510(3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,...)
Affinity DataEC50:  9.60nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254510BDBM50254510(3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,...)
Affinity DataIC50: 150nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed