BDBM50254570 (1S,9R,10S)-17-(cyclobutylmethyl)-10-hydroxy-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2,4,6-triene-4-carboxamide::CHEMBL517779

SMILES NC(=O)c1ccc2c(c1)[C@@]13CCCC[C@@]1(O)[C@@H](C2)N(CC1CCC1)CC3

InChI Key InChIKey=OUOLOWFYQLLGNP-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254570   

TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254570BDBM50254570((1S,9R,10S)-17-(cyclobutylmethyl)-10-hydroxy-17-az...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254570BDBM50254570((1S,9R,10S)-17-(cyclobutylmethyl)-10-hydroxy-17-az...)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254570BDBM50254570((1S,9R,10S)-17-(cyclobutylmethyl)-10-hydroxy-17-az...)
Affinity DataEC50:  3.80nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254570BDBM50254570((1S,9R,10S)-17-(cyclobutylmethyl)-10-hydroxy-17-az...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50254570BDBM50254570((1S,9R,10S)-17-(cyclobutylmethyl)-10-hydroxy-17-az...)
Affinity DataIC50: 30nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed