BDBM50254592 CHEMBL450954::N,N-dibutyl-4-chloro-5-methyl-1-(4-(phenylmethylsulfonamido)-2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-1H-pyrazole-3-carboxamide

SMILES CCCCN(CCCC)C(=O)c1nn(c(C)c1Cl)-c1ccc(NS(=O)(=O)Cc2ccccc2)cc1C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=TXYIKRKYZPDTCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254592   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254592(CHEMBL450954 | N,N-dibutyl-4-chloro-5-methyl-1-(4-...)
Affinity DataIC50:  3.15E+3nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 26 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254592(CHEMBL450954 | N,N-dibutyl-4-chloro-5-methyl-1-(4-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed