BDBM50254647 2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide::CHEMBL480809

SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=XUCAOVCVTZNGMX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254647   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed