BDBM50255144 CHEMBL4079391

SMILES CCN([C@H]1CCCNC1)c1ncc(C(N)=O)c2sc(cc12)-c1ccccc1

InChI Key InChIKey=WRRULJLHHSXDFQ-HNNXBMFYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255144   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50255144(CHEMBL4079391)
Affinity DataIC50:  35nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50255144(CHEMBL4079391)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50255144(CHEMBL4079391)
Affinity DataEC50:  110nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed