BDBM50255314 2-(5-((dimethylamino)methyl)-2-methylphenyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile::CHEMBL480222

SMILES Cc1ccc(CN(C)C)cc1-c1cc2c(Nc3ccc4[nH]ccc4c3C)c(C#N)cnc2s1

InChI Key InChIKey=JJFJVIQFBDEVSN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255314   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255314BDBM50255314(2-(5-((dimethylamino)methyl)-2-methylphenyl)-4-(4-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human full length PKCthetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255314BDBM50255314(2-(5-((dimethylamino)methyl)-2-methylphenyl)-4-(4-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255314BDBM50255314(2-(5-((dimethylamino)methyl)-2-methylphenyl)-4-(4-...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human full length PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed