BDBM50255426 (S)-N-((1s,4R)-4-tert-butylcyclohexyl)-1-oxo-2,3-diphenyl-2,7-diazaspiro[3.5]nonane-7-carboxamide::CHEMBL480629

SMILES CC(C)(C)[C@H]1CC[C@@H](NC(=O)N2CCC3(CC2)C(=O)N(c2ccccc2)[C@H]3c2ccccc2)CC1

InChI Key InChIKey=BVDKYCVYZYRHCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255426   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255426BDBM50255426((S)-N-((1s,4R)-4-tert-butylcyclohexyl)-1-oxo-2,3-d...)
Affinity DataIC50: 232nMAssay Description:Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of PMA-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50255426BDBM50255426((S)-N-((1s,4R)-4-tert-butylcyclohexyl)-1-oxo-2,3-d...)
Affinity DataIC50: 528nMAssay Description:Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed